ceesdekker.net Secrets

ceesdekker.net Secrets

Blog Article

Employing single-molecule optical and AFM imaging and drive-spectroscopy approaches, we search for to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our research pursuits incorporate:

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

Again in 1991, Sumio Iijima of your NEC Company experienced claimed the synthesis of carbon nanotubes. Band composition calculations suggested that these nanotubes could show metallic band conduction. This is able to be a significant advantage over the conducting polymers we experienced explored, which were being, in actual fact, disordered semiconductors featuring basically variable-vary hopping conductivity.

I can hardly imagine how I, to be a geneticist, would be able to master essential physics, not to mention compete at the top. How did you go over it?

Your browser isn’t supported any more. Update it to obtain the best YouTube practical experience and our most recent attributes. Find out more

SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological system for DNA loop extrusion

MATLAB codes for details processing are offered at . Julia codes utilized for numerical simulation are available at .

2011, first in vitro measurements of transportation throughout one biomimetic nuclear pore advanced; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination

This "Cited by" depend includes citations to the following articles or blog posts in Scholar. Those marked * can be different in the write-up while in the profile.

It was throughout this period that Dekker completed investigation on magnetic spin devices and on sounds in superconductors and semiconductors.

Considering that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Extra just cees dekker lately his research has centered on learning chromatin framework and cell division with micro organism on chip, whilst he is usually trying to finally Construct artificial cells from the bottom up.

‘That concerns the synthetic mobile, as A part of the Dutch BaSyC initiative. Craig Venter seemed top-down in People times and identified about 5 hundred genes that are minimally necessary for just a functioning cell. We wish to look bottom-up: how can we shift from a handful of molecules to an entire Organic method?

Skip to most important information Thank you for browsing nature.com. You might be employing a browser version with minimal support for CSS. To get the most beneficial expertise, we propose you use a more current browser (or transform off compatibility mode in Net Explorer).

Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in gray, the rim of the pore is highlighted in crimson, and also a 3D rendering of the movement with the DNA rod is exhibited.